Yossef Levy, PhD

VP CELL PRODUCTION
Yossef Levy is a member of the original Tel Aviv University research team that developed the NurOwn® technology platform, and he has been a core member of Cell-Gene company’s Research and Development team since the inception of the company.
He is also responsible for the company’s in-house cGMP production for clinical trials, technology transfer, and training to US-based cleanroom facilities. He leads the company’s workstream for co-development of bioreactor-based production scale-up. In addition, Dr. Levy supervises the company’s cleanroom operations and management, logistical coordination, and personnel training.
He received an MHA in Health Systems Management and a PhD in Neurobiology from Tel Aviv University, as well as an MSc in Clinical Pharmacy from Hebrew University. He is a licensed pharmacist.
Scroll to Top

Hi
Here you can see some frequently asked questions or contact us!

What passage are your cells?

Our human mesenchymal stem/stromal cells (hMSCs) are provided at a population doubling level (PDL) of 8-10 post-mononuclear isolation (Bone Marrow; Equivalent Passage 2) or 14-18 post-isolation from the perivascular region of Wharton’s Jelly (Umbilical Cord; Equivalent Passage 3). Due to variabilities of seeding and harvest densities we characterize our MSC “True Age” in terms of their PDL.

How often should I feed your cells?

A: There is no need to feed cells between passages. Our media is engineered to be a batch culture media, where no media exchange or feed is necessary when following our suggested protocols.

Are your vials sold from pooled donors?

No, we do not pool donors at any time during our production. Master Cell Banks (MCBs) are created from each donor source. Working Cell Banks (WCBs) are produced from our MCBs for general product sales.

What characterization do you provide for your hMSCs?

We characterize our hMSCs by following ISCT criteria: cell identity (surface marker expression), functional potency (angiogenic cytokine and IDO secretion), and trilineage differentiation (adipo-, osteo-, and chondrogenesis). This information is provided to allow customers to choose the optimal hMSC tissue type and donor for their specific application or target indication.