Actualités et questions fréquemment posées

Cell therapy

Cell/Stem cell therapy is the use of new cell/stem cells to replace exhausted or damaged cells in order to treat or prevent a disease or condition. The most widely used stem cell therapy is bone marrow transplantation for treatment of hematological disorders.

Mesenchymal stem cell

Mesenchymal stem cells are considered as adult stem cells, which firstly found in the bone marrow. MSCs are multipotent cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, and potentially other cell types. MSCs have been discovered for more than 50 years.

The source of mesenchymal stem cell

They can be isolated from other available tissues including bone marrow, adipose tissue, umbilical cord tissue, peripheral blood, cord blood etc.

Mechanism of action of mesenchymal stem cells

The mainly function these stem cells are the replacement of damaged cell and tissues. MSCs have strong immunomodulation and immune suppression properties so the allogeneic use of these cells is possible as well as autologous usage.

Tumor formation by human mesenchymal stem cells

There is no report about teratoma formation concern after MSCs transplantation in standard designed clinical studies.
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Here you can see some frequently asked questions or contact us!

What passage are your cells?

Our human mesenchymal stem/stromal cells (hMSCs) are provided at a population doubling level (PDL) of 8-10 post-mononuclear isolation (Bone Marrow; Equivalent Passage 2) or 14-18 post-isolation from the perivascular region of Wharton’s Jelly (Umbilical Cord; Equivalent Passage 3). Due to variabilities of seeding and harvest densities we characterize our MSC “True Age” in terms of their PDL.

How often should I feed your cells?

A: There is no need to feed cells between passages. Our media is engineered to be a batch culture media, where no media exchange or feed is necessary when following our suggested protocols.

Are your vials sold from pooled donors?

No, we do not pool donors at any time during our production. Master Cell Banks (MCBs) are created from each donor source. Working Cell Banks (WCBs) are produced from our MCBs for general product sales.

What characterization do you provide for your hMSCs?

We characterize our hMSCs by following ISCT criteria: cell identity (surface marker expression), functional potency (angiogenic cytokine and IDO secretion), and trilineage differentiation (adipo-, osteo-, and chondrogenesis). This information is provided to allow customers to choose the optimal hMSC tissue type and donor for their specific application or target indication.