Contact your RoosterBio representative for information on cGMP formats of RoosterReplenish-MSC.

RoosterReplenishTM-MSC-XF is a concentrated bioreactor feed for use in a fed-batch bioreactor process, enhancing media productivity to drive a radically cost-effective process that is less labor-intensive in small- and large-scale expansions of hMSCs in 3D bioreactors. RoosterReplenishTM-MSC-XF is designed to achieve high cell growth in microcarrier-based suspension cultures when paired with our xeno-free (XF) hMSCs (derived from multiple tissue types) and paired bioprocess media (RoosterNourish™-MSC-XF). Using RoosterNourish™-MSC-XF and RoosterReplenishTM-MSC-XF in a fed-batch system not only increases culture yield, it also minimizes the time required for media preparation, eliminates media exchange, and reduces the contamination risk associated with in-process manipulation. RoosterReplenishTM-MSC-XF boosts media productivity (millions of cells produced per Liter of media consumed) by up to 70%. Each 10 mL bottle of RoosterReplenishTM-MSC-XF can be used to supplement 500 mL of RoosterNourishTM-MSC-XF, with analogous version available for cGMP manufacturing.